Daniels: Where are the detectives who were first assigned?
Valchek: Dead. To me, anyway. I shipped them humps back to Burrell as fast as I could.

Frank Sobotka: Why the fuck didn't you tell me what was in that motherfucking can?
Spiros: Now you wanna know what's in the cans? Before you wanted to know nothing. Now you ask. Guns, OK? Drugs, whore, vodka, BMWs. Beluga caviar, or bombs, maybe? Bad terrorists with big nuclear bombs. I'm kidding you, Frank, it's a joke. But you don't ask ... because you don't wanna know.

Herc: How about you come on the raids tomorrow? Take a few doors for ol' time sake.
Kima: You takin' doors?
Herc: Yeah. Two houses an' a bar on Kane Street. C'mon Kima, mount up wit' us. I know you miss it.
Kima: I'm done rollin' around the gutter. I am inside now.
Herc: Oh, you're a house cat now, huh?
Kima: I made a promise.
Herc: I gotta say Kima, if you were a guy, and actually in some ways you're better than most of the guys I know. But if you were a guy, friends would buy you a beer and let you know.
Kima: Let me know what?
Herc: You're fuckin' whipped.
Kima: Whipped?
Herc: Pussy whipped within an inch of your life. I kid you not.

Horseface: [to Frank, while looking at a porn mag] Let me ask you something important. You like fake tits? I can't decide. Thus far, I'm undecided on fake tits.

Horseface: Damn, Frank.
Union Member: We just sat here and watched Nat Coxson take a shit all over you.
Horseface: And the shrivelled dick motherfucker that you are, you take it.
Sobotka: For your information, I wake up every morning with an angry blue vein diamond cutter. I was gonna enlighten the President of the local 47 on this particular point, and he chose to depart. Blue steel gentlemen. Three and a half inches of hard blue steel.

Kima: [to Daniels, about joining the new detail] I'll tell your wife if you tell mine.

Kima: Cool Lester Smooth... hey, what's happenin'?
Lester: Same fuck-ups in the same shit detail, workin' out of the same shithouse kind of office. You people lack for personal growth, you know that?

Landsman: It's all about self-preservation, Jimmy. Something you never learned.

Landsman: There is some charm to a woman in uniform. But the fact remains we work plain clothes in Homicide. Not to say that the clothes need be plain. For you, l would suggest some pantsuits muted in colour. Something to offset Detective Moreland's pinstriped, lawyerly affectations and the brash, tweedy impertinence of Detective Freamon.

Lester: [to "Non-English" speaking crewman] You cannot travel halfway around the world and not speak any motherfuckin' English.

Lester: Colonel, respectfully, did you just fuck me over without giving me half a chance to clear this case?
Rawls: Let's be clear, Detective Freamon. When I fuck you over, you'll know it. You'll be so goddamn certain, you won't need to ask the question.

Levy: You are amoral, are you not? You are feeding off the violence and the despair of the drug trade. You're stealing from those who themselves are stealing the lifeblood from our city. You are a parasite who leeches off--
Omar: Just like you, man.
Levy: --the culture of drugs... Excuse me, what?
Omar: I got the shotgun. You got the briefcase. It's all in the game, though, right?

McNulty [about the two hookers in the sting operation] There were two of them. I was outnumbered.

McNulty: [about Omar] He play you hard?
Bubbles: I go at him respectable. He put that goddamn shotgun in my face, man. I'm looking at two goddamn tubes of the Harbor Tunnel staring right at me. [McNulty laughs] Each one about yea-big. I damn near piss my pants.

McNulty: Fuck it, they chew you up, they gotta spit you back out.