Amanda Reese: Name names, and come clean. You help yourself, and your union.
Sobotka: Help my union? For 25 years we've been dyin' slow down there. Dry dock's rustin', piers standin' empty. My friends and their kids like we got the cancer. No life-line got thrown all that time, nothin' from nobody, and now you wanna help us? Help me?

Avon: [after Brianna confronts him about D'Angelo's suspicious suicide in prison] The fuck you even thinking? That I had something to do with it? That I could do that to my own kin? Is that what you think? The fuck is in your head Brie? I ain't do nothing to Dee. I ain't have shit to do with it.
Brianna: To do with what?

Avon: [to Stringer] I ain't no suit-wearin' businessman like you. You know, I'm just a gangster, I suppose. And I want my corners.

Avon: [to Stringer] Sunday truce been there as long as the game itself ..... I mean, you can do some shit and be like what the fuck, but hey, never on no Sunday.

Avon: Ayo what's up playboy? How come you wearin' that suit, B? For real its 85 fuckin' degrees out here and you try'na be like fuckin' Pat Riley
Proposition Joe : Look the part, be the part, motherfucker.

Avon: You know the difference between me and you? I bleed red and you bleed green. I look at you these days, String, you know what I see? I see a man without a country. Not hard enough for this right here and maybe, just maybe, not smart enough for them out there.

Beadie: All the guys at the bar, Jimmy, all the girls; they don't show up at your wake. Not because they don't like you. But because, they never knew your last name. Then a month later, someone tells them, "Oh, Jimmy died." "Jimmy who?" "Jimmy the Cop." "Ohhh," they say, "him". And all the people on the job, all those people you spent all the hours in the radio cars with, the guys with their feet up on the desk, tellin' stories, who shorted you on your food runs, who signed your overtime slips. In the end, they're not gonna be there either. Family, that's it. Family, and if you're lucky, one or two friends who are the same as family. That's all the best of us get. Everything else is just...

Beadie: World keeps turning.
Season 3

Bodie: [about Marlo] He's a cold motherfucker.
Poot: It's a cold world Bodie.
Bodie: Thought you said it was getting warmer.
Poot: The world goin' one way, people another yo'.

Bodie: [on killing Wallace] Look, the man gave the word, so we either step up or we step the fuck off. That's the game, yo.

Bodie: [to Namond] What you need school clothes for anyway? Yo ass stay suspended. If it wasn't for social promotion, yo ass would still be in Pre-k nigga...Prolly day care out this bitch.

Bodie: Come on with it, motherfuckers! I don't give a FUCK! [shoots at Chris] I'm right here! [shoots at Snoop] You ain't puttin' me in one of those empty-ass houses neither!

Bodie: Man, Boys Village ain't shit! I'm just too bad for that off-brand, lil' boy bullshit, man. It can't hold me.

Brother Mouzone: [to Avon, leading Avon to give up Stringer] What got you here is your word and your reputation. With that alone, you've still got an open line to New York. Without it, you're done.

Brother Mouzone: [to Cheese, after shooting him] Pellets in plastic. Rat shot. What you need to be concerned about is what's seated in the chamber now: a copper-jacketed, hollow point 120-grain hot street load of my own creation. So you need to think for just a moment and ask yourself: what do I have to do before this man raise up his gun again?