Grissom: You never get a second chance to make a first impression.
Sara: A square of nine dots on paper and you can only draw four lines to connect them... without the pen ever leaving the paper.
Grissom: Right. Think outside the box.

Grissom: You showered.
Catherine: Thanks for noticing Gil, you're very observant.
Grissom: [studying a surveillance tape and inadvertently blocking Catherine's view]) Yeah? Well ... I can't tell what I'm observing here. What does that look like?
Catherine: A five-foot-eleven workaholic.

Henry McFadden: Paige and I dated once or twice. She wasn't my type. If you haven't noticed... I'm in the system now. The talent pool's pretty deep.
Nick: She dumped you!

Janine Haywood: I told you I dropped them down the bathroom sink.
Brass: First time I heard that.
Janine Haywood: Look, I took two, gave Tony two and I accidentally dropped fifteen or twenty down the sink. It was an accident. You know, an accident? Haven't you ever spilled a drink?
Catherine: Not lately. We found fifty Xanax in Tony's stomach.
Janine Haywood: Don't pin that on me. I'd left.
Catherine: I'll tell you what you left -- your fingerprints all over the prescription bottle.
Janine Haywood: I went to the pharmacy waited in line picked up the prescription signed for it brought it back to the house. You know, Tony did nothing for himself except work and get high.
Brass: Got you a brand-new Mercedes, didn't it?
Janine Haywood: Yes, it did. And it'll buy me the dress I wear at Tony's funeral, too.
Brass: Look, when you left your half a house where did you go?
Janine Haywood: A friend's.
Brass: Well, let's get her on the line.
Janine Haywood: She's out of town.
Brass: Let me guess -- she's incommunicado.
Janine Haywood: That means you can't reach her? Yeah.

Lady Heather: I can read anyone who walks through this door and know their desires. Sometimes even before they do.

Lady Heather: It's just about knowing yourself, being strong and not taking any crap from powerful jerks who are used to giving it all day long.

Nick: Guy in the robe flagged down an officer.
Grissom: Guy in the robe is a monk, Nick.
Nick: Yeah. Well. [Nick looks at the monk for several seconds then turns back to Grissom] He's a quiet monk.

Nick: Hey.
Sara: Hey!
Nick: Wow. You look...
Sara: Happy?
Nick: Smug. Actually.

Nick: Hmm... hello, sweetheart.
Sara: End cap.
Nick: Pipe bomb.

Nick: How do you get one vic, let alone four... To sit still while you put a bullet between their eyes.
Grissom: They were praying.
Nick: Yeah, for mercy.
Grissom: For whoever was shooting them.

Nick: Sara, if you found a bomb in your car, would you close the hood?
Sara: No, I would back away fast. Um... maybe the hood dropped?
Nick: No way. BMW has built-in hood shocks.
Sara: Liar, liar, car on fire.

Nick: Sara?
Sara: Yeah?
Nick: You've got to get out more. [Turns and walks away]
Sara: [Shocked, she walks back down the hallway]

Nick: You just made yourself useful, my friend.
Greg: Oh yeah?
Nick: Yeah.
'Greg: How?

Nick: You know, it's easier to get a master's degree than a parking spot on campus.

Nick: You know, when I was 16, I begged my mom for a car. Swore she'd come through.
Sara: What happened?
Nick: Encyclopedia Britannica. (laughs) All 24 volumes. Still own them, still use them.