Scully: You believe it all, don't you?
Mulder: Why wouldn't I?
Scully: Mulder, did you see their eyes? If I were that stoned -
Mulder: Oooh... if you were that stoned, what?
Scully: Mulder, you could have shown that kid a picture of a flying hamburger and he would have told you that's exactly what he saw.

Scully: You set us up. You're in on this with Lucas Henry. This was a trap for Mulder because he helped put you away. Well, I came here to tell you that if he dies because of what you've done, four days from now, no one will be able to stop me from being the one that will throw the switch and gas you out of this life for good, you son of a bitch!

Scully: [Watching Dr. Berenbaum and Ivanov walking away] Well, think of it this way, Mulder. By the time there's another invasion of artificially-intelligent, dung-eating robotic probes from outer space, maybe their uber-children will have devised a way to save our planet.
Mulder: You know, I never thought I'd say this to you, Scully... but you smell bad.

Scully:...Flatworms are what are known as obligate endoparasites. They live inside of the host entering the body through ingestion of larvae or eggs. They are not creatures that go around attacking people.
Mulder: That's good. I didn't wanna tell Skinner his murder suspect was a giant bloodsucking worm.

Section Chief Blevins: Agent Mulder. What are his thoughts?
Scully: Agent Mulder believes we are not alone.

Section Chief Blevins: Are you familiar with the so-called X-Files?
Scully: I believe they have to do with unexplained phenomena.
Section Chief Blevins: More or less. The reason you're here, Agent Scully, is we want you to assist Mulder on these X-Files. You'll write field reports on your activities along with your observations on the validity of the work.
Scully: Am I to understand that you want me to debunk the X-Files Project, sir?
Section Chief Blevins: Agent Scully, we trust you'll make the proper scientific analysis.

Sheriff Daniels: Ninety-nine percent of the people in this world are fools ... and the rest of us are in great danger of contagion.

Sheriff Hamilton: [to Scully] Are you sure it was the brother you saw? Maybe it was the Fiji Mermaid who jumped in the sea and swam back to Fiji.
Mulder: [to Scully] Now you know how I feel.

Skinner: For every step you take they're three steps ahead.
Mulder: What about you, where do you stand?
Skinner: I stand right on the line you keep crossing.

Skinner: When I was eighteen, I, uh... I went to Vietnam. I wasn't drafted, Mulder, I- I enlisted in the Marine Corps the day of my eighteenth birthday. I did it on a blind faith. I did it because I believed it was the right thing to do. I don't know, maybe I still do. Three weeks into my tour, a ten-year-old North Vietnamese boy walked into camp covered with grenades and I, uh... I blew his head off from a distance of ten yards. I lost my faith. Not in my country or in myself, but in everything. There was just no point to anything anymore. One night on patrol, we were, uh... caught... and everyone- everyone fell. I mean, everyone. I looked down at my body from outside of it. I didn't recognize it at first. I watched the V.C. strip my uniform, take my weapon and I remained in this thick jungle... peaceful... unafraid... watching my- my dead friends. Watching myself. In the morning, the corpsmen arrived and put me in a body bag until... I guess they found a pulse. I woke in a Saigon hospital two weeks later. I'm afraid to look any further beyond that experience. You? You are not. Your resignation is unacceptable.
Mulder: (realizing) You. (exhales heavily) You gave me Cancer Man's location. You put your life in danger.
Skinner: Agent Mulder, every life, every day, is in danger. That's just life.

Skinner: There is no police report of this incident, Agent Mulder, and there is no body. You know that.
Mulder: Since I am unfamiliar with any such incident, sir, no, how would I know that?
Skinner: Knock it off!
Mulder: How's it feel? Constant denial of everything, questions answered with a question.
Skinner: I want to know what happened, damn it.
Mulder: Him. That's what happened. CANCER MAN! He's responsible for what happened to Scully!
Skinner: How do you know that?
Mulder: It's a rumor. Who is he?
Skinner: It's not your...
Mulder: Oh, you can have it all, you can have my badge, you can have the X-Files, just tell me where he is.
Skinner:And then what? He sleeps with the fishes? We're not the mafia, Agent Mulder. I know it's easy to forget but we work for the Department of Justice.
Mulder: That's what I want.
Skinner: Agent Scully was a fine officer. More than that... I liked her. I respected her. We all know the field we play on and we all know what can happen in the course of a game. If you were unprepared for all the potentials, then you shouldn't step on the field.

The Cigarette Smoking Man: Don't try and threaten me, Mulder. I've watched presidents die.

The Cigarette Smoking Man: We tell you only what you need to know.
Krycek: I think I have a right to know.
The Cigarette Smoking Man: You have no rights, only orders to be carried out. If you have a problem with that, we'll make other arrangements.

The Cigarette Smoking Man: What is this?
Skinner: This is where you pucker up and kiss my ass!
The Cigarette Smoking Man: Listen -
Skinner: (Interrupting) Now, you listen to me, you son of a bitch! This man's name is Albert Hosteen. You should remember that. Because if Agents Mulder and Scully come down with so much as a case of the flu, Albert is prepared to recite, chapter and verse, file for file, everything on your precious tape.
The Cigarette Smoking Man: It's a nice try, Skinner.
Skinner: I'm sure you're thinking Albert is an old man and there are plenty of ways you might kill him too. Which is why, in the ancient oral tradition of his people, he's told twenty other men the information on those files. So unless you kill every Navajo living in four states... that information is available with a simple phone call. (Smirks) Welcome to the wonderful world of high technology

The Son: Don't you want to live forever?
Mulder: Not if drawstring pants come back in style.