Kima: [to McNulty] How come they know you're police when they hook up with you. And they know you're police when they move in. And they know you're police when they decide to start a family with you. And all that shit is just fine until one day it ain't no more. One day, it's 'You should have a regular job.' and 'You need to be home at five o'clock'.
McNulty: "You need to stop fucking waitresses."

Kima: Bubs got some problems, but insincerity ain't one of them.
Walon: Shame is some tricky shit, ain't it? Makes you feel like you want to change, and then beats you back down when you think you can't.

Kima: Cool Lester Smooth... hey, what's happenin'?
Lester: Same fuck-ups in the same shit detail, workin' out of the same shithouse kind of office. You people lack for personal growth, you know that?

Kima: Fighting the war on drugs... one brutality case at a time.
Carver: Girl, you can't even think of calling this shit a war.
Herc: Why not?
Carver: Wars end.

Kima: How complex a code can it be if these knuckleheads are usin' it? Then again, what does it say about us if we can't break it?

Kima: You saw the murder?
Omar: Yeah.
Kima: You can ID this man Bird as the shooter of William Gant? And you ain't afraid to go into court downtown and testify against one of Barksdale's people?
Omar: Omar don't scare.

Landsman: [At McNulty's "wake"] He was natural po-lice. Yes, he was. And I don't say that about many people. Even when they're out here on the felt. I don't give that one up unless it happens to be true. Natural po-lice. ... [pretends to choke up] ... But, Christ, what an asshole!
...
Landsman: Jimmy, I say this seriously. If I was laying there dead on some Baltimore street corner, I'd want you standing over me, catching the case. Because, brother, when you were good, you were the best we had.
Bunk: Shit, if you were lying there dead on some corner, it probably was Jimmy that done ya.

Landsman: [to Bunk] Rawls and Foerster have crawled up my backside and they're gonna stay there until you find Dozerman's gun. Now, I would like it very much if I could unclench my ample ass cheeks, if you don't mind, and rid myself of that discomfort.

Landsman: [to Lester] We do not go looking for bodies. Especially moldering fucking John Does!

Landsman: [To McNulty] From everything we've given you, fire should be shootin' outta your ass. But there you sit, like a genital wart.

Landsman: It's all about self-preservation, Jimmy. Something you never learned.

Landsman: There is some charm to a woman in uniform. But the fact remains we work plain clothes in Homicide. Not to say that the clothes need be plain. For you, l would suggest some pantsuits muted in colour. Something to offset Detective Moreland's pinstriped, lawyerly affectations and the brash, tweedy impertinence of Detective Freamon.

Lester: [to "Non-English" speaking crewman] You cannot travel halfway around the world and not speak any motherfuckin' English.

Lester: Colonel, respectfully, did you just fuck me over without giving me half a chance to clear this case?
Rawls: Let's be clear, Detective Freamon. When I fuck you over, you'll know it. You'll be so goddamn certain, you won't need to ask the question.

Lester: From the looks of things, Stringer Bell's worse than a drug dealer.
Prez: He's a developer.