Locke: My walkabout. An adventure in the outback. Man against nature. But they wouldn't let me go. And I sat there yelling at them. Shouting at them that they couldn't tell me what I can't do. But they were right. I'm sick of imagining of what my life could be out of this chair, Helen. What it would be like to walk down the aisle with you because its not gonna happen. So if you need me to see more doctors, have more consults, if you need me to get out of this chair, I don't blame you. But I don't want you to spend your life waiting for a miracle because there is no such thing.

Locke: Nice work, Charlie. You make excellent bait!

Locke: Pull yourself together, son.
Charlie: It wouldn't be an irrational fear of bees if I could just pull myself together, would it?

Locke: Sure, you can yell at Boone 'til you're blue in the face, but all you're doing is giving him what he wants.
Shannon: Yeah? What's that?
Locke: Your attention.

Locke: Thank you Henry. Thank you for not leaving me.

Locke: The bullet went in one side, came out the other. I'd probably be dead if I still had a kidney there. Anything else?

Locke: The Man from Tallahassee? What is that some kind of code?
Ben: No John, unfortunately we don't have a code for "there is a man in my closet holding a gun to my daughter's head". Although we obviously should.

Locke: They've attacked us, sabotaged us, abducted us, murdered us... We're not the only people on this island and we all know it!

Locke: What are you doing?
Eko: I'm taking this back with us.
Locke: Why?
Eko: Because they may be important.
Locke: Important? I'm sorry, weren't you watching the same thing I was?
Eko: Yes, and I believe the work you have been doing is more important now than ever.
Locke: Work?
Eko: Pushing the button.
Locke: That's not work! That's a joke. Rats, in a maze, with no cheese.
Eko: We are being tested.
Locke: Tested?
Eko: The reason to do it, pushing the button, is not because we are told so in the film.
Locke: Well, then what is the reason, Mr. Eko?
Eko: We do it because we believe we are meant to. Isn't that the reason you pushed it, John?
Locke: I was never... meant to do anything! Every single second of my pathetic little life is as useless as that button! You think it's important? You think it's necessary? It's nothing, it's meaningless; and who are you to tell me that it's not?

Locke: What did one snowman say to the other snowman?
Desmond: "Smells like carrots."
Locke: Hello, Desmond.
Desmond: "Hello" yourself, box man.

Locke: What is this?
Richard: It's a compass.
Locke: What does it do?
Richard: It points north, John. Look, I wish I had time to be more sensitive about this because it's a lot to swallow, but you need to know it in order to do what you gotta do. So I'm just gonna say it, okay? The only way to save the island, John, is to get your people back here. The ones who left.
Locke: Jack, Kate? But the chopper was headed for the boat. The boat...
Richard: No, they're fine, John, and they're already home, so you have to convince them to come back.
Locke: How... How am I supposed to do that?
Richard: You're gonna have to die, John.
(The sky flashes again and Richard disappears)

Locke: What makes you think that I'm so special?
Charles Widmore: Because you are.

Locke: Where do you get electricity?
Ben: We have two big hamsters running around in this giant wheel in our secret underground lair.
Locke: Yeah, that's funny.

Locke: Who are you?
Gale: My name is Henry Gale. I'm from Minnesota and I crashed on this island just like you.

Locke: Why would Kate poison Michael?
Hurley: Well, you know, the whole fugitive thing. [Jack gawks at Hurley] He doesn't know? [Jack shakes his head]. Well how am I supposed to keep straight who knows what around here? I mean, Steve didn't even know about the polar bear.